{"id":406,"date":"2020-08-05T00:04:40","date_gmt":"2020-08-05T00:04:40","guid":{"rendered":"http:\/\/publichealth.sdsu.edu\/covid-19\/?page_id=406"},"modified":"2020-08-05T00:04:40","modified_gmt":"2020-08-05T00:04:40","slug":"immunity","status":"publish","type":"page","link":"https:\/\/vryheid.sdsu.edu\/index.php\/risky-situations\/immunity\/","title":{"rendered":"Immunity"},"content":{"rendered":"<p>After people have COVID-19, they probably become immune. \u00a0 Many convalescent patients developed SARS-CoV-2 neutralizing antibodies, IgM, and IgG, which decreased months later (<a href=\"https:\/\/thehill.com\/policy\/healthcare\/507043-virus-immunity-in-recovered-patients-may-be-gone-in-months-researchers-say\" target=\"_blank\" rel=\"noopener noreferrer\">Klar<\/a>; <a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2020.07.09.20149633v1\" target=\"_blank\" rel=\"noopener noreferrer\">Lei et al.<\/a>; <a href=\"https:\/\/www.nature.com\/articles\/s41591-020-0965-6\" target=\"_blank\" rel=\"noopener noreferrer\">Long et al.<\/a>; <a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2020.07.09.20148429v1\" target=\"_blank\" rel=\"noopener noreferrer\">Seow et al.<\/a>; <a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2020.07.14.20151126v1\" target=\"_blank\" rel=\"noopener noreferrer\">Wajnberg et al.<\/a>). \u00a0Memory T cells, CD4+ helper T cells, CD8+ killer T cells, and memory B cells, which are kinds of white cell lymphocytes, develop and provide longer-lasting immunity (<a href=\"https:\/\/us19.campaign-archive.com\/?u=ef98149bee3f299584374540a&amp;id=d53772e4a9\" target=\"_blank\" rel=\"noopener noreferrer\">Calhoun et al.<\/a>; <a href=\"https:\/\/www.cell.com\/cell\/pdf\/S0092-8674(20)30610-3.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Grifoni et al.<\/a>; <a href=\"https:\/\/www.nytimes.com\/2020\/07\/22\/health\/covid-antibodies-herd-immunity.html\" target=\"_blank\" rel=\"noopener noreferrer\">Mandavilli<\/a> \u201cCan you get COVID-19 again?\u201d; <a href=\"https:\/\/pdf.sciencedirectassets.com\/272197\/AIP\/1-s2.0-S1074761320301813\/main.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Ni et al.<\/a>; Resnick, Irfan; <a href=\"https:\/\/www.nature.com\/articles\/s41586-020-2456-9#citeas\" target=\"_blank\" rel=\"noopener noreferrer\">Robbiani et al.<\/a>; <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.06.29.174888v1\" target=\"_blank\" rel=\"noopener noreferrer\">Sekine et al<\/a>.; <a href=\"https:\/\/www.medrxiv.org\/content\/10.1101\/2020.05.13.20100636v1\" target=\"_blank\" rel=\"noopener noreferrer\">Thieme et al.<\/a>). \u00a0Consequently, patients with no detectable antibodies might still be immune (<a href=\"https:\/\/www.bbc.com\/future\/article\/20200716-the-people-with-hidden-protection-from-covid-19\" target=\"_blank\" rel=\"noopener noreferrer\">Gorvett<\/a>; <a href=\"https:\/\/www.vox.com\/2020\/7\/22\/21324729\/getting-covid-19-twice-immunity-antibodies-vaccine-herd-immunity\" target=\"_blank\" rel=\"noopener noreferrer\">Resnick, Irfan<\/a>).<\/p>\n<p>Some had COVID-19 symptoms for months, most testing positive for viral RNA, and some not (<a href=\"https:\/\/blogs.bmj.com\/bmj\/2020\/05\/05\/paul-garner-people-who-have-a-more-protracted-illness-need-help-to-understand-and-cope-with-the-constantly-shifting-bizarre-symptoms\/\" target=\"_blank\" rel=\"noopener noreferrer\">Garner<\/a>; <a href=\"https:\/\/www.nytimes.com\/2020\/07\/22\/health\/covid-antibodies-herd-immunity.html\" target=\"_blank\" rel=\"noopener noreferrer\">Mandavilli<\/a>; <a href=\"https:\/\/www.theatlantic.com\/health\/archive\/2020\/06\/covid-19-coronavirus-longterm-symptoms-months\/612679\/\" target=\"_blank\" rel=\"noopener noreferrer\">Yong \u201cCOVID-19 can last..\u201d<\/a>). Some apparently recovered, had no symptoms or viral RNA, and then showed\u00a0 symptoms and RNA again later.\u00a0 These probably were continuing the same disease case, and were not re-infected.\u00a0 Follow-up found none transmitting to contacts (<a href=\"https:\/\/www.cdc.go.kr\/board\/board.es?mid=a30402000000&amp;bid=0030\" target=\"_blank\" rel=\"noopener noreferrer\">Korea Centers for Disease Control<\/a>; <a href=\"https:\/\/www.nytimes.com\/2020\/07\/22\/health\/covid-antibodies-herd-immunity.html\" target=\"_blank\" rel=\"noopener noreferrer\">Mandavilli \u201cCan you get COVID-19 again?\u201d<\/a>).<\/p>\n<p>Doing controlled tests on humans to discover how many developed immunity would be difficult and not-very-ethical, so scientists have been experimenting on animals who get COVID-19 similarly to humans, including hamsters (<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32215622\/\" target=\"_blank\" rel=\"noopener noreferrer\">Chan, Zhang et al<\/a>; <a href=\"https:\/\/www.pnas.org\/content\/early\/2020\/06\/19\/2009799117.long\" target=\"_blank\" rel=\"noopener noreferrer\">Imai et al.<\/a>; <a href=\"https:\/\/www.nature.com\/articles\/s41586-020-2342-5\" target=\"_blank\" rel=\"noopener noreferrer\">Sia et al.<\/a>) and rhesus macaques (<a href=\"https:\/\/science.sciencemag.org\/content\/early\/2020\/05\/19\/science.abc4776.long\" target=\"_blank\" rel=\"noopener noreferrer\">Chandrashekar et al<\/a>; <a href=\"https:\/\/science.sciencemag.org\/content\/early\/2020\/07\/01\/science.abc5343.long\" target=\"_blank\" rel=\"noopener noreferrer\">Deng, Bao et al.<\/a>; <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/ame2.12108\" target=\"_blank\" rel=\"noopener noreferrer\">Yu, Qi et al.<\/a>)\u00a0 They found that some hamsters (<a href=\"https:\/\/www.pnas.org\/content\/early\/2020\/06\/19\/2009799117.long\" target=\"_blank\" rel=\"noopener noreferrer\">Imai et al.<\/a>) and rhesus macaques (<a href=\"https:\/\/science.sciencemag.org\/content\/early\/2020\/05\/19\/science.abc4776.long\" target=\"_blank\" rel=\"noopener noreferrer\">Chandrashekar et al<\/a>; <a href=\"https:\/\/science.sciencemag.org\/content\/early\/2020\/07\/01\/science.abc5343.long\" target=\"_blank\" rel=\"noopener noreferrer\">Deng, Bao et al.<\/a>) infected with COVID-19 developed antibodies and were protected against getting infected again.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>After people have COVID-19, they probably become immune. \u00a0 Many convalescent patients developed SARS-CoV-2 neutralizing antibodies, IgM, and IgG, which decreased months later (Klar; Lei et al.; Long et al.; Seow et al.; Wajnberg et al.). \u00a0Memory T cells, CD4+ helper T cells, CD8+ killer T cells, and memory B cells, which are kinds of [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":35,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-406","page","type-page","status-publish","hentry","post"],"_links":{"self":[{"href":"https:\/\/vryheid.sdsu.edu\/index.php\/wp-json\/wp\/v2\/pages\/406","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vryheid.sdsu.edu\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/vryheid.sdsu.edu\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/vryheid.sdsu.edu\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/vryheid.sdsu.edu\/index.php\/wp-json\/wp\/v2\/comments?post=406"}],"version-history":[{"count":0,"href":"https:\/\/vryheid.sdsu.edu\/index.php\/wp-json\/wp\/v2\/pages\/406\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/vryheid.sdsu.edu\/index.php\/wp-json\/wp\/v2\/pages\/35"}],"wp:attachment":[{"href":"https:\/\/vryheid.sdsu.edu\/index.php\/wp-json\/wp\/v2\/media?parent=406"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}