COVID-19 is probably not sexually transmitted. SARS-CoV-2 RNA was not found in vaginas of infected women, perhaps because vaginal tissue lacks angiotensin-converting enzyme 2 (ACE2), the cell receptor for SARS-CoV-2 (Cui et al.). ACE2 is more highly expressed in testes than ovaries, so testes might serve as reservoirs for SARS-CoV-2, and might explain why more men were severely infected than women (Shastri et al.). No SARS-CoV-2 RNA was found expressed prostatic secretions (EPS) of infected men (Quan et al.), or in semen (Pan X et al.). So COVID-19 is probably not transmitted sexually, but sexual interactions could transmit it through the other routes described above.